Why NAD+ Infusions Can Cause Initial Fatigue (and Why It’s Actually a Good Sign) in Terre Haute & Shelbyville, Indiana
Wondering why NAD+ infusions sometimes cause fatigue? Learn the science behind it, what to expect, and why clients in Terre Haute & Shelbyville see long-term benefits.
If NAD+ Boosts Energy, Why Do Some People Feel Tired at First?
One of the most common questions we hear at our med spas in Terre Haute and Shelbyville is:
“If NAD+ is supposed to boost my energy, why do I feel tired right after an infusion or injection?”
It may seem confusing — but the truth is, this temporary fatigue is actually a normal (and positive) part of the process.
The Science Behind NAD+ and Fatigue
NAD+ plays a vital role in cellular energy production. When you receive a NAD+ infusion or injection, your body suddenly has more of this crucial molecule available. That “kick-start” can temporarily overwhelm your cells as they begin repairing, detoxing, and balancing.
Here’s what’s happening behind the scenes:
Cellular Repair Takes Energy – Your body is directing resources into healing and DNA repair.
Toxin Release – As cells repair, stored toxins may be released, which can make you feel sluggish.
Metabolic Shift – Your body is adjusting to a higher level of energy efficiency — similar to how you might feel sore after a workout, even though it’s helping you get stronger.
How Long Does NAD+ Fatigue Last?
For most clients in Terre Haute and Shelbyville, fatigue after NAD+ therapy is short-lived — usually just a few hours to a day. Once the body adjusts, the benefits shine through:
Increased, steady energy
Better mental clarity
Improved sleep and recovery
Enhanced mood and focus
Tips for Managing Initial Fatigue
If you do feel a little wiped out after treatment, here are a few helpful tips:
Stay Hydrated – Water helps flush toxins and supports your metabolism.
Rest if Needed – Listen to your body and give it time to adjust.
Plan Ahead – Schedule your first NAD+ session on a lighter day, just in case.
Stay Consistent – Many clients find that after the first 1–2 treatments, they no longer feel post-infusion fatigue.
Why This Is Actually a Good Sign
That brief fatigue is your body’s way of saying:
💡 “I’m working hard behind the scenes to repair and restore.”
Think of it like a detox or the soreness after exercise — a temporary discomfort that leads to long-term health benefits.
Why Indiana Clients Trust Our NAD+ Therapy
At our med spas in Shelbyville and Terre Haute, we don’t just administer NAD+ and send you on your way. We:
Educate you on what to expect (including possible initial fatigue).
Provide personalized dosing so your treatment is tailored to your needs.
Support you before, during, and after your session to ensure you feel confident and cared for.
👉 Curious about NAD+ therapy? Book your consultation in Terre Haute or Shelbyville, Indiana today and experience how this powerful treatment can transform your energy and wellness.